Development of prediction models for carbapenem-resistant <i>Klebsiella pneumoniae</i> acquisition and prognosis in adult patients.

ABSTRACT:

Objectives

To explore the risk factors and clinical outcomes of carbapenem-resistant Klebsiella pneumoniae (CRKP) infection and establish nomograms to predict the probability of CRKP infection and mortality in adult patients.

Methods

Patients infected with KP from August 2019 to April 2021 in a tertiary hospital in Shanghai were enrolled. Risk factors associated with CRKP and 30-day mortality were identified using multivariate logistic regression analysis and Cox regression analysis.

Results

Overall, 467 patients with KP infection were enrolled, wherein 210 (45.0%) patients were infected with CRKP and 257 (55.0%) patients with carbapenem-susceptible K. pneumoniae (CSKP). Five factors, namely Charlson's Comorbidity Index (CCI) ≥ 3, the use of central veno

SUBMITTER: Yao H 

PROVIDER: S-EPMC11573532 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature