Association between the serum albumin-creatinine ratio and 28-day intensive care unit mortality among patients with sepsis: a multicenter retrospective cohort study.

ABSTRACT:

Introduction

Sepsis is a substantial global health challenge with a considerable disease burden. Despite advancements in sepsis research, the mortality rates associated with this condition remain high. The relationship between the serum albumin-to-creatinine ratio (sACR) and mortality in patients with sepsis remains unclear. Therefore, this study aimed to investigate the association between the sACR and 28-day mortality in intensive care unit (ICU) patients with sepsis.

Methods

In this retrospective cohort study, we used data sourced from the eICU Collaborative Research Database. The primary exposure variable was sACR, and the primary outcome measure was mortality within 28 days after ICU admission. Statistical analyses included univariate and multivariate logistic regressio

SUBMITTER: Lin W 

PROVIDER: S-EPMC11573561 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature