Ratios of calcium to citrate administration in blood transfusion for traumatic hemorrhage: A retrospective cohort study.

ABSTRACT:

Background

Massive transfusion with citrated blood products causes hypocalcemia, which is associated with mortality. Recognition of this problem has led to increased calcium administration; however, the optimal dosing is still unknown.

Study design and methods

This retrospective, single-center study included level 1 trauma patients in 2019 and 2020 who underwent an operation within 12 h of arrival and received a transfusion. Preoperative and intraoperative administrations were totaled to calculate the ratio of administered calcium to the number of blood transfusions for each patient. The citrate content of each blood component was estimated to calculate a second ratio, the ratio of administered calcium to administered citrate. Receiver Operating Characteristic (ROC) curves w

SUBMITTER: Alghanem H 

PROVIDER: S-EPMC11573635 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature