Distinct brain and neurocognitive transformations after bariatric surgery: a pilot study.

ABSTRACT:

Background

Obese patients have worse outcomes after surgery and are at increased risk for perioperative neurocognitive disorders (PND). Our aim was to detail the cognitive trajectories of patients undergoing bariatric surgery (BS) and map distinct structural brain changes using magnetic resonance imaging (MRI) to better understand the association between the vulnerable brain, surgery, and the arc of PND.

Methods

Prospective pilot study with longitudinal comprehensive cognitive assessments and MRI were performed on obese patients scheduled for BS. We analyzed baseline cognitive function and high-resolution T1-/T2-weighted brain images on 19 obese patients [age, 54 (9) years, BMI, 40 (36, 42) kg m^-2] and compared with 50 healthy control subjects [age, 52 (6) years;

SUBMITTER: Roy B 

PROVIDER: S-EPMC11573770 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature