In vitro fertilization and long-term child health and development: nationwide birth cohort study in Japan.

ABSTRACT: The aim of this study is to compare long-term health outcomes between IVF-conceived children and non-IVF-conceived children in Japan, in the context of strong recommendation for single embryo transfer. Using data from a nationwide birth cohort linked with perinatal database, this study analyzed 2140 children born in Japan in May 2010. It compared child health and development outcomes up to 9 years of age between IVF-conceived and non-IVF-conceived children (binary exposure). A Poisson regression with robust variance to estimate the risk ratios for the association between IVF and various long-term child health and developmental outcomes. After adjusting for confounding factors, no significant differences were observed between IVF-conceived and naturally conceived children for most outcomes,

SUBMITTER: Matsumoto N 

PROVIDER: S-EPMC11573831 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature