Hypothetical Interventions on Cardiovascular Health Metrics for Abnormal Cognitive Aging: An Application of the Parametric g-formula in the CLHLS Cohort Study with 12 Years Follow-Up.

ABSTRACT:

Background

Abnormal cognitive aging is closely related to dementia.

Objectives

This study aimed to estimate the effect of cardiovascular health (CVH) metrics on abnormal cognitive aging.

Design

A longitudinal cohort study.

Setting

Participants were recruited from the Chinese Longitudinal Health Longevity Survey.

Participants

A total of 3298 participants aged ≥65 years with normal cognitive performance at baseline were included.

Measurements

Cognitive performance was measured by the Chinese version of the Mini-Mental State Examination (MMSE). CVH was assessed with six metrics, including hypertension, diabetes, exercise, body mass index (BMI), diet, and smoking. Group-based trajectory model was used to identify the trajectory groups of cognitive agi

SUBMITTER: Huang S 

PROVIDER: S-EPMC11573857 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature