Variability of quality-of-life measurements and reporting in randomised controlled trials of pancreatic cancer: a systematic review.

ABSTRACT:

Objectives

This systematic review aims to evaluate the methodology used in pancreatic cancer (PC) randomised controlled trials (RCTs) measuring quality of life (QOL) and focuses on the type, frequency, survey compliance and duration of these assessments.

Design

Systematic review of PC RCTs measuring QOL.

Data sources

A search of PubMed.gov and ClinicalTrials.gov was conducted for PC RCTs measuring QOL from inception to 21 March 2023. Only phase III RCTs were included. Studies were excluded if QOL was not measured, the study was phase I/II, in the second-line setting or unavailable in English. Data were independently extracted by two reviewers in a standardised fashion.

Primary and secondary outcome measures

Primary outcomes included the type of QOL instrument u

SUBMITTER: Tushoski-Aleman GW 

PROVIDER: S-EPMC11574412 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature