A one-year hospital system review of plasma next-generation sequencing in a mixed population.

ABSTRACT:

Objective

To describe the use of plasma next-generation sequencing (NGS) and determine if it provided additional information from routine tests or lead to change in antimicrobial management.

Design and setting

This retrospective cohort study evaluated patients with a NGS test performed who were admitted to a hospital health system in the greater Houston area between May 2022 and May 2023.

Patients

In total, 143 NGS tests were ordered in the span of one year for 135 unique patients. Most patients were ≥ 18 years (74.1%), White/Caucasian (43.7%), male (61.5%), and immunocompetent (54.1%). Eight patients had repeat tests during the study period, four being after an initial rejected test, and the rest being greater than 7 days from the initial test.

Results

Of the

SUBMITTER: Drake TC 

PROVIDER: S-EPMC11574590 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature