Bokeelamides: Lipopeptides from Bacteria Associated with Marine Egg Masses.

ABSTRACT: Moon snails (family: Naticidae) lay egg masses that are rich in bacterial species distinct from the surrounding environment. We hypothesized that this microbiome chemically defends the moon snail eggs from predation and pathogens. Herein, we report the discovery of bokeelamides, new lipopeptides from the egg mass-associated bacterium, Ectopseudomonas khazarica, which were discovered using mass spectrometry (MS)-based metabolomics. The structures of the bokeelamides were elucidated using two-dimensional (2D) nuclear magnetic resonance (NMR), tandem MS, Marfey's, and genomic analyses.

SUBMITTER: Campbell R 

PROVIDER: S-EPMC11574851 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature