Association between nickel exposure and diabetes risk: an updated meta-analysis of observational studies.

ABSTRACT:

Objective

The results of epidemiological studies on the association between nickel exposure and diabetes remain controversial. Therefore, an update meta-analysis was conducted to examine the association between urinary nickel levels and diabetes risk, and to focus on whether there is an association between blood nickel levels and diabetes risk.

Methods

Relevant studies were comprehensively searched from PubMed, Web of Science, and Wanfang databases from their inception to July 2024. The random-effects model was utilized to determine pooled Standard Mean Difference (SMD) and 95% confidence intervals (CIs), with stratified and sensitivity analyses also performed. Heterogeneity between studies was assessed using I ² statistic, while publication bias was evalua

SUBMITTER: Lu H 

PROVIDER: S-EPMC11574963 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature