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Association of insulin resistance surrogate indices and erectile dysfunction: a systematic review and meta-analysis.


ABSTRACT:

Background

Erectile dysfunction (ED) has been linked to insulin resistance (IR), with various surrogate indices being used to assess this association. This systematic review and meta-analysis aimed to evaluate the relationship between IR indices and the incidence and severity of ED.

Methods

A comprehensive search across PubMed, Embase, Web of Science, and Scopus was carried out. Required data were extracted and meta-analyzed. The Newcastle-Ottawa Scale (NOS) was employed to evaluate the studies' risk of bias. Sensitivity analyses and meta-regressions were conducted to explore heterogeneity and the impact of confounding variables.

Results

Seventeen studies with a total of 3810 patients with ED and 8252 without ED were included. Meta-analysis revealed that males with ED

SUBMITTER: Jalali S 

PROVIDER: S-EPMC11574999 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature