Diastolic dysfunction and risks of heart failure and death in long-term adult cancer survivors.

ABSTRACT:

Background

Cancer survivors face elevated risks of heart failure (HF) and death, with cardiac dysfunction being a significant concern. Current evaluations often emphasize systolic function while insufficiently addressing diastolic function. This study aims to investigate the prevalence of diastolic dysfunction and assess its prognostic implications in long-term cancer survivors.

Methods

We analyzed participants from the Atherosclerosis Risk in Communities (ARIC) Study with complete echocardiographic assessments and documented cancer histories. Diastolic function was classified by guideline criteria: normal (≤ 1 abnormal parameter), indeterminate (2 abnormal parameters), and dysfunction (≥ 3 abnormal parameters). The primary outcomes were incident HF and all-cause death. Dias

SUBMITTER: Yu R 

PROVIDER: S-EPMC11575149 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature