Investigating social orienting in children with Phelan-McDermid syndrome and 'idiopathic' autism.

ABSTRACT:

Background

Phelan-McDermid syndrome (PMS) is a rare genetic syndrome characterized by developmental delay/intellectual disability, absent or delayed speech, physical dysmorphic features and high rates of autistic features. However, it is currently unknown whether people with PMS have similar neurocognitive atypicalities to those previously identified in idiopathic autism. Disruption in social orienting has previously been suggested as an early hallmark feature of idiopathic autism that impacts social learning and social interaction.

Methods

This study used a semi-naturalistic task to explore orienting to social versus non-social stimuli and its relation to clinical features in individuals diagnosed with PMS, autism, and neurotypical children recruited in the United States an

SUBMITTER: San Jose Caceres A 

PROVIDER: S-EPMC11575217 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature