E.PathDash, pathway activation analysis of publicly available pathogen gene expression data.

ABSTRACT: E.PathDash facilitates re-analysis of gene expression data from pathogens clinically relevant to chronic respiratory diseases, including a total of 48 studies, 548 samples, and 404 unique treatment comparisons. The application enables users to assess broad biological stress responses at the KEGG pathway or gene ontology level and also provides data for individual genes. E.PathDash reduces the time required to gain access to data from multiple hours per data set to seconds. Users can download high-quality images such as volcano plots and boxplots, differential gene expression results, and raw count data, making it fully interoperable with other tools. Importantly, users can rapidly toggle between experimental comparisons and different studies of the same phenomenon, enabling them to judge t

SUBMITTER: Taub L 

PROVIDER: S-EPMC11575265 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature