Intranasal insulin for the treatment of olfactory dysfunction: a protocol for a systematic review and meta-analysis.

ABSTRACT:

Introduction

Olfactory dysfunction (OD) is a prevalent nasal affliction that has detrimental effects on the patients' quality of life and safety. Conventional therapeutic strategies have various limitations such as high costs, prolonged treatment durations and adverse side effects. Intranasal insulin is a novel intervention for the management of OD. To date, few systematic reviews have been conducted to evaluate the efficacy of this intervention. This study aims to critically assess the therapeutic efficacy and safety profile of intranasal insulin administration in patients with OD.

Methods and analysis

A systematic literature search will be performed on several databases, including PubMed, the Cochrane Central Register of Controlled Trials, Embase, SinoMed and China Nationa

SUBMITTER: He X 

PROVIDER: S-EPMC11575286 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature