Metabolomics and proteomics analyses of Chrysanthemi Flos: a mechanism study of changes in proteins and metabolites by processing methods.

ABSTRACT:

Background

Chrysanthemi Flos is a traditional Chinese medicine with a long history of medicinal use. Prior research suggests that the intrinsic composition of Chrysanthemi Flos is affected by shade-drying and oven-drying methods. Nevertheless, the effects of these methods on the proteins and metabolites of Chrysanthemi Flos have not been extensively studied.

Methods

The TMT (tandem mass tag) quantitative proteomics method and the LC-MS/MS (liquid chromatography-tandem mass spectrometry) non-targeted metabolomics method were used to systematically study the differences in the proteins and metabolites during the process of drying Chrysanthemi Flos in the shade and an oven.

Results

Differentially accumulated metabolites and abundant proteins were primarily enriched in th

SUBMITTER: Zhang W 

PROVIDER: S-EPMC11575428 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature