Dynamic satellite-parent liposome networks for quantitative microreactions.

ABSTRACT: The hierarchical assembly of liposomes into interconnected networks forms the basis for creating rudimentary artificial multicellular systems. Each vesicle performs specialized functions both temporally and spatially, replicating the complexity of living tissues. Controlling the size and number of liposomes in artificial multicellular systems and their dynamic interactions are necessary for quantitative bioprocesses but remain challenging. Here, we develop a satellite-parent liposome network-a central parent liposome surrounded by smaller satellite liposomes. This structure spontaneously forms during the dewetting transition of microfluidically prepared complex double emulsions. Intriguingly, the adhesion strength between the satellites and the parent liposome can be tuned using environmen

SUBMITTER: Tian JQ 

PROVIDER: S-EPMC11575560 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature