Pd(ii)-catalyzed enantioselective C-H olefination and photoregulation of sterically hindered diarylethenes.

ABSTRACT: Sterically hindered diarylethenes with intrinsic chirality have shown great potential in chiral signal regulation, light-controlled liquid crystals (LCs), etc. Their unique enantiospecific phototransformation between axial chirality of ring-open isomers and central chirality of ring-closed isomers can break through the bottleneck of interference between multiple chiral centers in traditional chiral diarylethenes. However, these intrinsic chiral diarylethenes require necessary chiral resolution through preparative chiral HPLC, typically resulting in limited separation efficiency and production scale. Here, we present an enantioselective olefination strategy to directly construct intrinsic chiral diarylethenes from a prochiral sterically hindered diarylethene, achieving high yields an

SUBMITTER: Zhang G 

PROVIDER: S-EPMC11575610 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature