Genomic variants associated with type 2 diabetes mellitus among Filipinos.

ABSTRACT: Type 2 diabetes mellitus leads to debilitating complications that affect the quality of life of many Filipinos. Genetic variability contributes to 30% to 70% of T2DM risk. Determining genomic variants related to type 2 diabetes mellitus susceptibility can lead to early detection to prevent complications. However, interethnic variability in risk and genetic susceptibility exists. This study aimed to identify variants associated with type 2 diabetes mellitus among Filipinos using a case-control design frequency matched for age and sex. A comparison was made between 66 unrelated Filipino adults with type 2 diabetes mellitus and 121 without. Genotyping was done using a candidate gene approach on genetic variants of type 2 diabetes mellitus and its complications involving allelic association an

SUBMITTER: C Cutiongco-de la Paz EM 

PROVIDER: S-EPMC11575783 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature