Sexual function following risk-reducing salpingo-oophorectomy: a prospective cohort study.

ABSTRACT:

Background

Increased access to and indications for genetic testing will lead to more women undergoing risk-reducing salpingo-oophorectomy (RRSO), with a potential impact on sexual function.

Aim

Our objective was to prospectively investigate (1) sexual function in women with pathogenic variant (PV) in BRCA1/2 genes, before and 1 year after RRSO, and to compare with a healthy age-matched control group and (2) to study if testosterone levels correlate with sexual functioning after RRSO.

Methods

A prospective observational follow-up study of 43 BRCA1/2-PV carriers planned for RRSO and 73 healthy-age matched controls. Data including personal medical history, the Female Sexual Function Index (FSFI) and blood samples for analysis of testosterone by tandem mass

SUBMITTER: von Kartaschew AE 

PROVIDER: S-EPMC11576125 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature