Novel biocompatible magnetron-sputtered silver coating for enhanced antibacterial properties and osteogenesis in vitro.

ABSTRACT: Peri-implant infection is a serious complication in orthopedic surgery. This study aimed to reduce the incidence of peri-implant infection by developing a durable and safe antibacterial silver coating. We compared the antibacterial properties and process controllability of various coating techniques to identify the most effective method for silver coating. We refined substrate treatment techniques and coating thicknesses through antibacterial and scratch tests. Scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDS) were used to analyze the coating's morphology and composition. Micron-sized magnetron sputtering silver coating samples underwent in vitro antibacterial testing, cytotoxicity testing, silver ion release testing, and osteogenic testing using membrane co

SUBMITTER: Juma T 

PROVIDER: S-EPMC11576870 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature