The association between salivary oxytocin, age, and puberty in children with and without OCD.

ABSTRACT: The oxytocin system has been thought to contribute to obsessive-compulsive disorder (OCD). Few studies, only involving adults, have investigated this hypothesis and have found inconsistent results regarding oxytocin system activity and OCD. We investigated whether salivary oxytocin concentrations differed between children and adolescents with and without OCD and qualified our comparative analysis by investigating the possible covariates age, pubertal stage, and sex. Participants included 113 children and adolescents (8-17 years) with OCD and 88 children and adolescents without any previous or current psychiatric disorder and their parents (254 parents included). Salivary oxytocin concentrations were measured in children and parents with enzyme-linked immunosorbent assay (ELISA). Statistica

SUBMITTER: Mora-Jensen AC 

PROVIDER: S-EPMC11576962 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature