Fabrication and X-ray microtomography of sandwich-structured PEEK implants for skull defect repair.

ABSTRACT: Bone defects pose a significant risk to human health. Medical polyetheretherketone (PEEK) is an excellent implant material for bone defect repair, but it faces the challenge of bone osteoconduction and osseointegration. Osteoconduction describes the process by which bone grows on the surface of the implant, while osseointegration is the stable anchoring of the implant achieved by direct contact between the bone and the implant. Bone defects repair depends on the implant's three-dimensional spatial structure, including pore size, porosity, and interconnections to a great extent. However, it is challenging to fabricate the porous structures to meet specific requirements and to characterize them without causing damage. In this study, we designed and fabricated sandwich-like PEEK implants mimi

SUBMITTER: Qi ML 

PROVIDER: S-EPMC11577077 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature