Incidence of pneumococcal disease in children in Germany, 2014-2019: a retrospective cohort study.

ABSTRACT:

Background

Novel, expanded valency pneumococcal conjugate vaccines (PCVs) are in development to reduce the burden of pneumococcal disease (PD) in children. To understand the potential value of new vaccines in Germany, this study estimated the residual burden of PD in children < 16 years old from 2014 to 2019, using administrative health data from a large German claims database.

Methods

Outpatient and inpatient cases of all-cause pneumonia (ACP), pneumococcal pneumonia (PP) and invasive pneumococcal disease (IPD) were identified in the InGef database. Incidence rates (IRs) with 95% confidence intervals (CI) were calculated as number of episodes/person-years (PY) at risk. The Mann-Kendall test assessed time trends in incidence.

Results

There were no significant trends i

SUBMITTER: Weaver J 

PROVIDER: S-EPMC11577647 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature