High pertussis circulation among infants, children and adolescents in Abidjan, Cote d'Ivoire.

ABSTRACT:

Background

Whooping cough due to Bordetella pertussis (BP) and/or B. parapertussis (BPP) is a highly contagious infection sometimes fatal for infants. Africa accounts for the largest share of cases and deaths worldwide. To evaluate pertussis circulation, we conducted a hospital-based prospective study (PS) including household contact-cases investigation (CCS) and a sero-epidemiological cross-sectional study (SECS).

Methods

The PS, in which Bordetella diagnostics (qPCR) were performed, included infants aged ≤6 months presenting with ≥5 days of cough associated with one pertussis-like symptom. CCS was performed using qPCR and serology regardless of clinical signs. In the SECS, serology was performed in children aged 3-15 years with primary pertussis immunization.

Results

SUBMITTER: Soumahoro MK 

PROVIDER: S-EPMC11578514 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature