Different sodium concentrations of noncancerous and cancerous prostate tissue seen on MRI using an external coil.

ABSTRACT:

Background

Sodium (²³Na) MRI of prostate cancer (PCa) is a novel but underdocumented technique conventionally acquired using an endorectal coil. These endorectal coils are associated with challenges (e.g., a nonuniform sensitivity profile, limited prostate coverage, patient discomfort) that could be mitigated with an external ²³Na MRI coil.

Purpose

To quantify tissue sodium concentration (TSC) differences within the prostate of participants with PCa and healthy volunteers using an external ²³Na MRI radiofrequency coil at 3 T.

Materials and methods

A prospective study was conducted from January 2022 to June 2024 in healthy volunteers and participants with biopsy-proven PCa. Prostate ²³Na MRI was acquired on a 3-T PET/MRI scan

SUBMITTER: Tan JL 

PROVIDER: S-EPMC11578593 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature