Systemic inflammation and health outcomes in patients receiving treatment for atherosclerotic cardiovascular disease.

ABSTRACT:

Background and aims

The burden and outcomes of inflammation in patients with atherosclerotic cardiovascular disease (ASCVD) are not well defined beyond the controlled settings of trials and research cohorts.

Methods

This was an observational study of ASCVD adults undergoing C-reactive protein testing in Stockholm's healthcare (2007-21). After excluding C-reactive protein tests associated with acute illness or medications/conditions that bias C-reactive protein interpretation, systemic inflammation was evaluated over a 3-month ascertainment window. Determinants of C-reactive protein ≥ 2 mg/L were explored with logistic regression. C-reactive protein categories were compared via negative-binomial/Cox regression for subsequent healthcare resource utilization and occurrence of m

SUBMITTER: Mazhar F 

PROVIDER: S-EPMC11578643 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature