Chronological outcomes of renal function after adrenalectomy in patients with primary aldosteronism across age groups.

ABSTRACT:

Background

Patients with primary aldosteronism present with renal function decline after unilateral adrenalectomies. Our study aimed to assess the evolution of renal function after adrenalectomy in patients with primary aldosteronism across different age groups and to identify risk factors for postoperative renal function deterioration.

Methods

We included 210 patients with primary aldosteronism categorized into three age groups: <40, 40-60, and ≥60 years old. We followed up the patients for 1 month, 1 year, and 5 years after adrenalectomy to assess outcomes. Multivariate analyses were performed to identify predictors of renal function deterioration, and a univariate logistic regression analysis was used to assess the relationship between KCNJ5 mutation status and the

SUBMITTER: Ma Y 

PROVIDER: S-EPMC11578701 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature