The effect of a low-carbohydrate diet on subcutaneous adipose tissue in females with lipedema.

ABSTRACT:

Introduction

Lipedema is a common, yet underdiagnosed, subcutaneous adipose tissue (SAT) disorder. The main characteristics are SAT expansion in the lower extremities and arms, pain, and tenderness to palpation. It remains unknown if a low-carbohydrate diet (LCD) influences SAT in females with lipedema.

Objectives

To evaluate the effect of a LCD low-energy diet, compared to a low-fat isoenergetic control diet, on calf subcutaneous adipose tissue area, muscle area, SAT/muscle ratio, calf circumference and body composition in females with lipedema.

Subjects/methods

Adult females with obesity and lipedema were randomized to 1,200 kcal/day diets, either LCD or control (75 and 180 g/day of carbohydrates, respectively) for 8 weeks. Body composition was measured with bioelec

SUBMITTER: Lundanes J 

PROVIDER: S-EPMC11578713 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature