Efficacy analysis of neuroprotective drugs in patients with acute ischemic stroke based on network meta-analysis.

ABSTRACT:

Objective

This network meta-analysis aims to explore the efficacy and safety of neuroprotective agents in patients with ischemic stroke and attempts to identify which drug is the most effective in improving outcomes for patients with acute ischemic stroke (AIS) through a ranking method.

Methods

We comprehensively searched the PubMed, Medline, Embase, Web of Science, and Cochrane library databases from their establishment to 30 June 2024. Data were extracted from the studies identified, and their quality was assessed using the Cochrane risk-of-bias tool or the Newcastle-Ottawa Scale (NOS). The outcome measures were for a favorable prognosis, based on the modified Rankin Scale score (mRS) or National Institutes of Health Stroker Scale (NIHSS) score, mortality, and adverse effe

SUBMITTER: Li M 

PROVIDER: S-EPMC11578817 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature