Impact of fat intake on [¹⁸F]AlF-NOTA-FAPI-04 uptake in normal abdominal organs.

ABSTRACT:

Purpose

[¹⁸F]AlF-NOTA-FAPI-04 demonstrates significant physiological uptake in the gallbladder and biliary tract system, representing a limitation of this positron emission tomography (PET) tracer. The aim of this study was to evaluate the impact of milk consumed prior to a PET/CT scan on [¹⁸F]AlF-NOTA-FAPI-04 uptake in normal abdominal organs.

Materials and methods

A total of 86 patients who underwent [¹⁸F]AlF-NOTA-FAPI-04 PET/CT imaging took part in this single-center retrospective clinical study at the Hunan Cancer Hospital between December 2020 and August 2021. Patients were divided into two groups according to their pre-PET scan diet: treated group, who consumed 250 mL of milk 10 ± 5 min after the tracer injection, while the control grou

SUBMITTER: Dai J 

PROVIDER: S-EPMC11578823 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature