Natural course of ulcerative colitis in China: Differences from the West?

ABSTRACT:

Background and aims

Whether the natural course of ulcerative colitis (UC) in mainland China is similar or different from that in Western countries is unknown, and data on it is limited. We aimed to provide a comprehensive description of the natural course of UC in China and compare it with Western UC patients.

Methods

Based on a prospective Chinese nationwide registry of consecutive patients with inflammatory bowel diseases, the medical treatments and natural history of UC were described in detail, including disease extension, surgery, and neoplasia. The Cox regression model was used to identify factors associated with poor outcomes.

Results

A total of 1081 UC patients were included with a median follow-up duration of 5.3 years. The overall cumulative exposure was 99.

SUBMITTER: Wan J 

PROVIDER: S-EPMC11578846 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature