Delirium risk and mortality in people with pre-existing severe mental illness: a retrospective cohort study using linked datasets in England.

ABSTRACT:

Background

Delirium is a severe neuropsychiatric syndrome caused by physical illness, associated with high mortality. Understanding risk factors for delirium is key to targeting prevention and screening. Whether severe mental illness (SMI) predisposes people to delirium is not known. We aimed to establish whether pre-existing SMI diagnosis is associated with higher risk of delirium diagnosis and mortality following delirium diagnosis.

Methods

A retrospective cohort and nested case-control study using linked primary and secondary healthcare databases from 2000-2017. We identified people diagnosed with SMI, matched to non-SMI comparators. We compared incidence of delirium diagnoses between people with SMI diagnoses and comparators, and between SMI subtypes; schizophrenia, bipo

SUBMITTER: Bauernfreund Y 

PROVIDER: S-EPMC11578903 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature