Simultaneous analysis of several plasticizer classes in different matrices by on-line turbulent flow chromatography-LC-MS/MS.

ABSTRACT: The development of methodologies for the determination of plasticizers is essential for assessing the environmental and human impact resulting from the use of plastics. A fast analytical method with on-line purification based on turbulent flow chromatography (TFC) coupled to tandem mass spectrometry (MS-MS) has been developed for the analysis of ten phthalates, four alternative plasticizers (including adipates and citrates), and 20 organophosphate esters (OPEs). The method has been validated for the determination of plasticizers across different matrices. Analytical parameters showed acceptable recoveries ranging between 50 and 125%, RSDs lower than 20%, and mLODs of 0.001-2.08 ng g^-1 wet weight (ww), 0.002-0.30 ng g^-1, and 0.001-0.93 ng m^-3 for foodstuffs,

SUBMITTER: Fernandez-Arribas J 

PROVIDER: S-EPMC11579108 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature