Prognostic analysis of early-onset and late-onset nasopharyngeal carcinoma: a retrospective study.

ABSTRACT:

Purpose

There are few studies on early-onset and late-onset nasopharyngeal cancer (EONPC and LONPC, defined as cancers in those aged < 50 and ≥ 50 years, respectively). This study aimed to determine the clinical and survival characteristics of patients with NPC in these two age groups.

Methods

This study involved patients diagnosed with NPC between 2000 and 2018, as per the Surveillance, Epidemiology, and End Results (SEER) database, and in our institution from 2014 to 2017. The clinicopathological characteristics, treatment modalities, and survival outcomes of patients with EONPC and LONPC were analyzed and compared.

Results

A total of 2943 patients from the SEER database and 833 domestic patients from our center were enrolled in the study. The EONPC group showed a b

SUBMITTER: Li P 

PROVIDER: S-EPMC11579260 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature