Endoscopic features of the duodenal pyloric gland adenoma: A case series of 14 patients.

ABSTRACT:

Background

Pyloric gland adenoma (PGA) is a distinct subtype of duodenal adenoma. PGA has been increasingly recognized as a histologically and molecularly distinct entity; however, its endoscopic features have not been precisely described. This study aims to investigate the endoscopic characteristics of duodenal PGA, including the association of their putative precursors, Brunner's gland hyperplasia (BGH), and gastric epithelial heterotopia/metaplasia (GEM/H).

Methods

This study was a single-center, retrospective case series. Fourteen consecutive patients with duodenal PGA were retrieved from the pathological database. PGA was diagnosed according to the World Health Organization classification.

Results

The median tumor size was 22.5 mm (range: 12-40 mm), and 79% of ca

SUBMITTER: Uozumi T 

PROVIDER: S-EPMC11579376 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature