Automating life science labs at the single-cell level through precise ultrasonic liquid sample ejection: PULSE.

ABSTRACT: Laboratory automation technologies have revolutionized biomedical research. However, the availability of automation solutions at the single-cell level remains scarce, primarily owing to the inherent challenges of handling cells with such small dimensions in a precise, biocompatible manner. Here, we present a single-cell-level laboratory automation solution that configures various experiments onto standardized, microscale test-tube matrices via our precise ultrasonic liquid sample ejection technology, known as PULSE. PULSE enables the transformation of titer plates into microdroplet arrays by printing nanodrops and single cells acoustically in a programmable, scalable, and biocompatible manner. Unlike pipetting robots, PULSE enables researchers to conduct biological experiments using single

SUBMITTER: Zhang P 

PROVIDER: S-EPMC11579414 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature