Paired associative stimulation improves motor function in the upper extremity in chronic incomplete spinal cord injury: a corroborative study.

ABSTRACT:

Objective

To corroborate findings suggesting that spinally targeted paired associative stimulation improves upper extremity motor function in chronic incomplete spinal cord injury.

Design

Prospective interventional study.

Subjects

Five adults with chronic tetraplegia.

Methods

Participants received paired associative stimulation, combining peripheral nerve stimulation and navigated transcranial magnetic stimulation towards 1 arm (16 1-h sessions during 4 consecutive weeks, targeting the 3 large nerves). Manual muscle testing (MMT) was performed in 23 muscles in each arm, at 3 time points (pre-stimulation, t0; the week following the stimulation period, t1; and 4-5 weeks post-stimulation, t2). Additionally, grip strength and changes in the Canadian Occupational Pe

SUBMITTER: Wahlgren C 

PROVIDER: S-EPMC11579534 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature