Characteristics of non-randomised studies of drug treatments: cross sectional study.

ABSTRACT:

Abstract

Objective

To examine the characteristics of comparative non-randomised studies that assess the effectiveness or safety, or both, of drug treatments.

Design

Cross sectional study.

Data sources

Medline (Ovid), for reports published from 1 June 2022 to 31 August 2022.

Eligibility criteria for selecting studies

Reports of comparative non-randomised studies that assessed the effectiveness or safety, or both, of drug treatments were included. A randomly ordered sample was screened until 200 eligible reports were found. Data on general characteristics, reporting characteristics, and time point alignment were extracted, and possible related biases, with a piloted form inspired by reporting guidelines and the target trial emulation framework.

Results

SUBMITTER: Yaacoub S 

PROVIDER: S-EPMC11579539 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature