Microbiome-Based Colon Cancer Patient Stratification and Survival Analysis.

ABSTRACT:

Background

Colorectal cancer (CRC) is any cancer that starts in the colon or the rectum and presents a significant health concern. It is the third most diagnosed and the second deadliest cancer, with an estimated 153,020 new cases and 52,550 deaths in 2023. The severity of colon cancer may be attributed to its ability to avoid the host immune system and growth suppressors, its asymptomatic nature in the early stages, its association with a continually ageing population and unfavourable diet and obesity. The composition of the gut microbiome plays an important role in the development of CRC and presents as an important target in early detection and in predicting treatment outcomes in CRC. This study aims to identify microbiome-specific derived clusters in CRC patients and conduct su

SUBMITTER: Smyth J 

PROVIDER: S-EPMC11579663 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature