The impact of pathogenic <i>BRCA1/2</i> tumor mutation status on high grade serous epithelial ovarian cancer survival outcome: A multicenter study from Indonesia.

ABSTRACT:

Introduction

Ovarian cancer is still a major health problem in Indonesia. development of breast cancer gene-related personalized medicine to increase the survival outcome of epithelial ovarian cancer patients in Indonesia is expected to be achieved. This research aims to evaluate the impact of pathogenic breast cancer gene 1 and breast cancer gene 2 tumor mutation on high-grade serous epithelial ovarian cancer survival outcome.

Methods

This study is an observational analytic study, using a historical cohort study design. A total of 68 from 144 patients diagnosed with International Federation of Gynecology and Obstetrics 2014 stage IIB-IV high-grade serous epithelial ovarian cancer between January 1st, 2015 until March 31st, 2021, at three centers in Jakarta. Next-generation

SUBMITTER: Sutrisno S 

PROVIDER: S-EPMC11580090 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature