Clinical features and risk factors for development of post-infectious bronchiolitis obliterans in children.

ABSTRACT:

Background

Post-infectious bronchiolitis obliterans (PIBO) is a severe form of chronic obstructive lung disease secondary to severe respiratory tract infections. Knowledge of pediatric PIBO development-associated risk factors may improve selection of appropriate early therapeutic interventions.

Objective

The aim of this study was to describe the clinical characteristics of children diagnosed with PIBO, and identify the risk factors for development of PIBO after adenovirus pneumonia.

Methods

First, a retrospective observational study was performed of 308 pediatric patients with PIBO (ages < 5 years) that revealed high frequencies of non-invasive/invasive ventilation, co-infection, and atopic conditions. Subsequently, we retrospectively reviewed 131 patients (ages < 5 y

SUBMITTER: Xu W 

PROVIDER: S-EPMC11580501 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature