Industrial diet intervention modulates the interplay between gut microbiota and host in semi-stray dogs.

ABSTRACT:

Background

The gut microbiota and derived metabolites play a key role in regulating host physiology. Diet is identified as a key regulatory factor of the microbiota composition and, potentially, of subsequent functionalities. Demonstrating the role of diet may be complex as most human studies are cross-sectional and dietary intervention is often accompanied by hygienic changes. The objective of the present study was to investigate the impact of an industrial diet on the modulation of the microbiota and targeted functionalities using a canine "natural" model.

Results

We carried out a controlled dietary trial in a cohort of Tunisian semi-stray dogs. We made a transition from a natural diet to an industrial kibble diet and monitored the composition of the fecal microbiota, the

SUBMITTER: Rhimi S 

PROVIDER: S-EPMC11580502 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature