Association between Weight-Adjusted Waist Index and Depression in NAFLD: the modulating roles of sex and BMI.

ABSTRACT:

Background

The Weight-Adjusted Waist Index (WWI) is a novel indicator of obesity that accurately reflects body composition. However, the association between WWI and depression in patients with non-alcoholic fatty liver disease (NAFLD) remains unclear. This study aims to explore this relationship through a nationally representative cross-sectional analysis.

Methods

This study included adult participants diagnosed with NAFLD from NHANES 2017-2020. WWI was calculated as the waist circumference (cm) divided by the square root of body weight (kg). NAFLD diagnosis relied on vibration-controlled transient elastography (VCTE) with a controlled attenuation parameter (CAP) exceeding 248 dB/m to indicate hepatic steatosis. Depression was assessed using the Patient Health Questionnaire-

SUBMITTER: Zhang J 

PROVIDER: S-EPMC11580667 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature