Diagnostic value of arterial spin labeling for Alzheimer's disease: A systematic review and meta-analysis.

ABSTRACT:

Background

Arterial spin labeling (ASL) is a magnetic resonance imaging (MRI) technique that offers a non-invasive approach for measuring cerebral blood perfusion (CBF). CBF serves as a marker of neuronal activity, and ASL has demonstrated the potential to detect reductions in CBF associated with early-stage neurodegenerative diseases like Alzheimer's disease (AD). Consequently, ASL has garnered growing interest as a potential diagnostic tool for AD. Despite the promise of ASL for diagnosing AD, there is a paucity of data regarding the pooled specificity and sensitivity of this technique in this context. The purpose of this systematic review and meta-analysis is to identify the accuracy of ASL in the diagnosis of AD with international clinical diagnosis as the gold standard.

Met

SUBMITTER: Zhang XY 

PROVIDER: S-EPMC11581220 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature