ABO-identical versus incompatible platelet transfusion in patients with intracranial hemorrhage.

ABSTRACT:

Background

Patients with spontaneous and traumatic intracranial hemorrhage (ICH) are frequently transfused platelets to treat thrombocytopenia, platelet function defects, and reverse antiplatelet drugs. ABO-identical platelet transfusion has been suggested to lead to higher post-transfusion platelet increments compared to major-ABO incompatible transfusion. We hypothesized that patients who received ABO-identical transfusion would have higher post-transfusion platelet increments and superior neurologic outcomes.

Methods

Adults with traumatic or non-traumatic ICH from January 1st 2018 to December 31st 2022 were identified using electronic medical records and international classification of disease (ICD)-10 codes. Patients were excluded if they lacked a platelet count within 2

SUBMITTER: Dunn LK 

PROVIDER: S-EPMC11581237 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature