The diagnostic performance of cochlear endolymphatic hydrops and perilymphatic enhancement in stratifying Meniere's disease probabilities: A meta-analysis of semi-quantitative MRI-based grading systems.

ABSTRACT:

Background

The diagnosis of Meniere's Disease (MD) presents significant challenges due to its complex symptomatology and the absence of definitive biomarkers. Advancements in MRI technology have spotlighted endolymphatic hydrops (EH) as a key pathological marker, necessitating a reevaluation of its diagnostic utility amidst the need for standardized and validated MRI-based grading scales.

Methods

Our meta-analysis scrutinized the diagnostic efficacy of semi-quantitative MRI-based cochlear endolymphatic hydrops (EH) and perilymphatic enhancement (PLE) grading systems in delineating clinically relevant discriminations: "Spotting" the shift from normal or asymptomatic ears to possible/probable MD (pMD), "Confirming" the progression to definite MD (dMD), and "Establishing" the p

SUBMITTER: Azarpey N 

PROVIDER: S-EPMC11581247 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature