Short-Term Dual Antiplatelet Therapy After Drug-Eluting Stenting in Patients With Acute Coronary Syndromes: A Systematic Review and Network Meta-Analysis.

ABSTRACT:

Importance

The optimal duration of dual antiplatelet therapy (DAPT) in patients with acute coronary syndromes (ACS) undergoing percutaneous coronary intervention (PCI) remains under debate.

Objectives

To analyze the efficacy and safety of DAPT strategies in patients with ACS using a bayesian network meta-analysis.

Data sources

MEDLINE, Embase, Cochrane, and LILACS databases were searched from inception to April 8, 2024.

Study selection

Randomized clinical trials (RCTs) comparing DAPT duration strategies in patients with ACS undergoing PCI were selected. Short-term strategies (1 month of DAPT followed by P2Y12 inhibitors, 3 months of DAPT followed by P2Y12 inhibitors, 3 months of DAPT followed by aspirin, and 6 months of DAPT followed by aspirin) were compared w

SUBMITTER: Carvalho PEP 

PROVIDER: S-EPMC11581547 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature