Frequency of Screening and Spontaneous Breathing Trial Techniques: A Randomized Clinical Trial.

ABSTRACT:

Importance

The optimal screening frequency and spontaneous breathing trial (SBT) technique to liberate adults from ventilators are unknown.

Objective

To compare the effects of screening frequency (once-daily screening vs more frequent screening) and SBT technique (pressure-supported SBT with a pressure support level that was >0-≤8 cm H2O and a positive end-expiratory pressure [PEEP] level that was >0-≤5 cm H2O vs T-piece SBT) on the time to successful extubation.

Design, setting, and participants

Randomized clinical trial with a 2 × 2 factorial design including critically ill adults who were receiving invasive mechanical ventilation for at least 24 hours, who were capable of initiating spontaneous breaths or triggering ventilators, and who were receiving a fractional

SUBMITTER: Burns KEA 

PROVIDER: S-EPMC11581551 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature