Development and Validation of a Clinical Score to Predict Epilepsy After Cerebral Venous Thrombosis.

ABSTRACT:

Importance

One of 10 patients develop epilepsy in the late phase after cerebral venous thrombosis (CVT) diagnosis but predicting the individual risk is difficult.

Objective

To develop and externally validate a prognostic score to estimate the individual risk of post-CVT epilepsy.

Design, setting, and participants

This observational cohort study included both retrospective and prospective patients enrolled from 1994 through 2022. For development of the DIAS3 score, data from the International CVT Consortium (n = 1128), a large international hospital-based multicenter CVT cohort, were used. For validation, data from 2 independent multicenter cohorts, the ACTION-CVT (n = 543) and the Israel CVT study (n = 556), were used. Of 2937 eligible, consecutively enrolled adult pa

SUBMITTER: Lindgren E 

PROVIDER: S-EPMC11581563 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature